ABSTRACT
A type of endomitotic chromosome reduplication in the interphase stage of cell cycle was found in lymphocyte cultures of couples with spontaneous abortions. To find out the presence of this anomaly chromosomal analysis was performed in a series of 20 women with repeated spontaneous abortions and their husbands. Demographic data was also collected from them. Out of 40 individuals, a 27 years male whose wife has experienced three spontaneous abortions was found to have Endoreduplication. His wife was normal with 46, XX chromosomal complement.
ABSTRACT
Cytogenetic analysis of 70 primary amenorrhea cases revealed normal chromosomal constitution (46, XX-71.43%) in 50 and abnormal karyotype in 20 (28.57%) cases examined. Among the abnormal cases, there were 4 with 45, X (5.71%), 11 (15.71) with 45, X / 46, XX; 1 each with mosaicism of 45, X / 47, XXX and 45, XX/47, XXX and 47, XXX (1.43%) constitution. The remaining 2 cases with 46, XY constitution had testicular feminization syndrome.